Cyanobacterial Production of Biopharmaceutical and Biotherapeutic Proteins
نویسندگان
چکیده
منابع مشابه
Production of biopharmaceutical proteins by yeast
Production of recombinant proteins for use as pharmaceuticals, so-called biopharmaceuticals, is a multi-billion dollar industry. Many different cell factories are used for the production of biopharmaceuticals, but the yeast Saccharomyces cerevisiae is an important cell factory as it is used for production of several large volume products. Insulin and insulin analogs are by far the dominating bi...
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Multiproduct manufacturing facilities running on a campaign basis are increasingly becoming the norm for biopharmaceuticals, owing to high risks of clinical failure, regulatory pressures and the increasing number of therapeutics in clinical evaluation. The need for such flexible plants and cost-effective manufacture pose significant challenges for planning and scheduling, which are compounded b...
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Mammalian expression systems, due to their capacity in post-translational modification, are preferred systems for biopharmaceutical protein production. Several recombinant protein systems have been introduced to the market, most of which are under clinical development. In spite of significant improvements such as cell line engineering, introducing novel expression methods, gene silencing and pr...
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methods for detection, quantitation and characterization of antibody responses have been developed. The results can provide intelligence for patient safety and treatment as well as increased knowledge about the immune response to the drug. However, assays for antibodies in biological fluids are susceptible to a wide range of technical difficulties in addition to scientific challenges in their i...
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ژورنال
عنوان ژورنال: Frontiers in Plant Science
سال: 2020
ISSN: 1664-462X
DOI: 10.3389/fpls.2020.00237